Days Set Up
Monday - Friday
Analytic Time

28 days

MiChart Code
PAI1 (Serpine1) Mutation Detection
Soft Order Code
PAI1M

Test Updated:

Synonyms

Plasminogen activator inhibitor-1 (PAI-1) deficiency
PAI1MS
PAI1 (SERPINE1) Mut Det Shadow
PAI1M
PAI1 (Serpine1) Sequencing
Plasminogen Activator Inhibitor 1 Mutation
PAI-1 Inhibitor Mutation Detection
Serpin E1 Mutation
PLANH1 Mutation
Endothelial Plasminogen Activator Inhibitor Mutation

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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

Learn about how to properly label and where to ship specimens.

Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

Test FAQ

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Test Overview

Test Methodology

Exon 4 of the PAI-1 (SERPINE1) gene is amplified using specific primers, and bidirectionally sequenced using a fluorescent method.

Test Usage

Analysis for the presence of the c.699_700dupTA frameshift mutation in the PAI-1 (SERPINE1) gene, in patients with clinical features consistent with Plasminogen Activator Inhibitor-1 (PAI-1) deficiency.

Reference Range

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Instructions

Collect specimen in a lavender top tube. Send intact specimen within 24 hours if stored at room temperature or within 5 days if stored refrigerated. Include the patient's family history, pedigree, and ethnicity on the test requisition. Obtaining informed consent from the patient prior to genetic testing is strongly recommended. If desired, a UMHS Request and Consent for Genetic Testing form can be obtained from the MMGL Molecular Genetics Laboratory by contacting the MLabs Client Services Center at 800-862-7284 or online at https://mlabs.umich.edu/sites/default/files/2020-01/file/pci-mmgl_infor….

Lavender Top Tube
Normal Volume
5 - 10 mL EDTA whole blood
Minimum Volume
2 mL EDTA whole blood

Billing Information

CPT Code
81403
Pro Fee Code
 
Insurance Auth Info
 
LOINC
 

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.