Update Type: Test Code Change
Test Updated: 12/23/2025
Test Overview
Test Methodology
Liquid chromatography Tandem Mass Spectrometry (LC-MS/MS)
Test Usage
Monitoring therapeutic efficacy/compliance in serum specimens of patients who are prescribed oxycodone and/or oxymorphone.
Reference Range *
Oxycodone: 10-100 ng/mL; Noroxycodone: Metabolite of oxycodone; Oxymorphone Metabolite of oxycodone: 1.0-8.0 ng/mL when used as sole therapy; Noroxymorphone: Metabolite of oxymorphone
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Test Details
Days Set Up
Wednesday
Analytic Time
2 - 4 days
Soft Order Code
MMLR
MiChart Code
Oxycodone Level
Synonyms
- OxyContin, Serum or Plasma
- Percocet, Serum or Plasma
- Percodan, Serum or Plasma
- Roxicodone, Serum or Plasma
Laboratory
Sendout
Reference Laboratory
Mayo OXYDS
Section
Special Testing
Specimen Requirements
Collection Instructions
Collect specimen in a red top tube, NO SST. Centrifuge, aliquot serum into a plastic vial and refrigerate.
Normal Volume
1 mL serum
Minimum Volume
1 mL serum
Storage Temperature
Refrigerated preferred, frozen acceptable
Additional Information
Test performed by Mayo Clinic Laboratories.
Billing
CPT Code
G0480/80365
Fee Code
32155
NY State Approved
No