Test Overview
Test Methodology


Test Usage

This real-time polymerase chain reaction test provides qualitative detection of non-variola Orthopoxvirus (ie, monkeypox) DNA in swab specimens of skin or genital lesions present in individuals with suspected monkeypox.

Reference Range *


Test Limitations

Additional Information: Source information should include anatomical site of collection. Each lesion should be ordered separately. To avoid cross contamination, do not combine multiple sites into one order.

Test Details
Days Set Up
Monday - Friday
Analytic Time

2 - 5 days

Soft Order Code
Reference Laboratory
Special Testing
Specimen Requirements
Collection Instructions

1. Swab or brush the lesion vigorously (not obtaining adequate DNA can result in inconclusive results) with 2 sterile swabs.
2. Place both swabs in same 1 tube containing VTM.
3. Do not send swabs in glass tubes, vacutainer tubes, tubes with push caps, or paper swab sleeves.
4. Refrigerate specimens within 1 hour after collection.

Normal Volume
2 swabs
Minimum Volume
2 swabs
Storage Temperature
Refrige preferred, frozen acceptable
Rejection Criteria
Swab submission tubes containing foam, gel, charcoal, or any liquid besides viral transport media
Glass transport tubes
Swabs submitted in paper swab packaging sleeve
Swabs submitted in UTM (universal transport media)
Wood swabs
Foam tipped swabs
Cotton swabs
Bloody specimens
Additional Information

Test performed by Mayo Clinic Laboratories

CPT Code
NY State Approved