Test Overview
Test Methodology

Isoelectric Focusing (IEF) with IgG Immunoblot Detection

Reference Range *

CSF Olig Bands Interpretation: <4 bands. A finding of 4 or more cerebrospinal fluid (CSF)-specific bands (i.e., bands that are present in CSF but are absent in serum) is consistent with multiple sclerosis. The presence of oligoclonal band is unrelated to disease activity.

Test Limitations

Increased intrathecal Ig synthesis may occur in other infammatory CSF diseases and, therefore, this assay is not specfic for MS.

Test Details
Days Set Up
Monday - Saturday
Analytic Time

2 - 4 days

Soft Order Code
OLIG
MiChart Code
Oligoclonal Banding, CSF (Mayo)
Synonyms
  • CSF Gamma Globulin Banding
  • Electrophoresis, CSF
  • MS
  • Multiple Sclerosis
  • Multiple Sclerosis (MS)
  • O Bands
  • Oliband
  • Protein Electrophoresis, CSF
  • Sclerosis
  • OLIGOCLONAL BANDS - CSF
  • OLI BAND
  • MS Profile
Laboratory
Sendout
Reference Laboratory
Mayo OLIG (8017)
Section
Special Testing
Specimen Requirements
Collection Instructions

Collect both blood and CSF; specimens must be collected within 1 week of each other. Collect blood in an SST tube and aliquot serum into a plastic vial. Refrigerate serum and CSF specimens.

Yellow Top Tube
Normal Volume
0.5 mL serum AND 0.5 mL CSF
Minimum Volume
0.4 mL serum AND 0.4 mL CSF
Storage Temperature
Refrigerated: 7 days, Ambient: 14 dayss, Frozen: 14 days.
Additional Information

Test sent to Mayo Medical Laboratories.

Billing
CPT Code
83916 x2
Fee Code
AA011
LOINC
2873-8
NY State Approved
No