Test Overview
Test Methodology
Liquid Chromatography - Tandem Mass Spectrometry (LC-MS/MS)
Test Usage
Monitor therapeutic drug levels; monitor patient compliance; evaluate nortriptyline toxicity
Reference Range *
Therapeutic: 70 - 170 ng/mL. Therapeutic ranges are for specimens drawn at trough (ie, immediately before next scheduled dose). Levels may be elevated in non-trough specimens.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Test Details
Days Set Up
Tuesday, Thursday, Sunday
Analytic Time
3 - 5 days
Soft Order Code
NOTRP
MiChart Code
Nortriptyline Level
Synonyms
- Aventyl
- Pamelor
- Tricyclics, Nortriptyline
- NORT
- NORTRIPTYLINE
- NORTRIPTYLINE LEVEL
Laboratory
Sendout
Reference Laboratory
Mayo NOTRP
Section
Special Testing
Specimen Requirements
Collection Instructions
Collect blood in a red top tube immediately before next scheduled dose (minimum 12 hours after last dose); do not use SST tube. Centrifuge, aliquot serum or plasma into plastic vial within 2 hours of collection, and refrigerate.
Alternate Specimen
In house test NORT down/discontinued 7/8/2022, send to Mayo NOTRP.
Normal Volume
1 mL serum
Minimum Volume
0.25 mL serum
Rejection Criteria
SST or PST tube not acceptable.
Additional Information
Test sent to Mayo Clinic Laboratories.
Billing
CPT Code
80335
Fee Code
AB138
LOINC
3872-9