Test Overview
Test Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Test Usage

Monitoring of tobacco use.

Reference Range *

Nicotine: <3 ng/mL; Cotinine: <3 ng/mL.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Sunday
Analytic Time

2 - 5 days

Soft Order Code
NICOS
MiChart Code
Nicotine and Metabolites, Serum
Synonyms
  • Cotinine, Serum
  • NICOTINE AND METABOLITES, S
  • COTS
  • NICO
  • TRANS COT
  • COTININE
  • NICOTINE
  • TRANS-3-OH COTININE
Laboratory
Sendout
Reference Laboratory
Mayo NICOS (82509)
Section
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in a red top tube (SST tube is not acceptable). Centrifuge, aliquot serum into a plastic vial and refrigerate.

Normal Volume
0.8 mL serum
Minimum Volume
0.5 mL serum
Storage Temperature
Refrigerated preferred, ambient or frozen are acceptable
Rejection Criteria
SST tube is not acceptable
Additional Information

Test sent to Mayo Medical Laboratories.

Billing
CPT Code
80323
Fee Code
22013
LOINC
3853-9