Test Overview
Test Methodology

Indirect Immunofluorescence

Test Usage

Detection of circulating anti-neutrophil antibodies in suspected cases of autoimmune neutropenia. The work-up of individuals having febrile, nonhemolytic transfusion reactions.

Reference Range *

Negative (reported as positive or negative).

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

No distinction can be made between autoantibodies and alloantibodies. This test is not useful for diagnosis of neutropenia caused by marrow suppression by drugs or tumors.

Test Details
Days Set Up
Tuesday, Wednesday, Friday
Analytic Time

7 - 16 days

Soft Order Code
MiChart Code
Granulocyte Ab S (Sendout)
  • Leukocyte Antibody
  • Anti-Leukocyte Antibody
  • Granulocyte Antiboides, Serum
  • Anti-Neutrophil Antibody
  • Anti-PMN Antibody
  • Neutrophil Antibodies
  • Anti-Granulocyte Antibody
  • LAGG
Reference Laboratory
Mayo LAGGT (8976)
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in a red top tube; do not use SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate or freeze.

Normal Volume
1.5 mL serum
Minimum Volume
0.3 mL serum
Rejection Criteria
SST tube not acceptable.
Additional Information

Test sent to Mayo Medical Laboratories. University of Michigan registered patient specimens sent to American Red Cross, North Central Blood Services, Neutrophil Serology Laboratory.

CPT Code
Fee Code