Days Set Up
Monday - Friday
Analytic Time

6 - 12 days

Soft Order Code

Test Updated:


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Test Overview

Test Methodology


Test Usage

Neurotensin is a 13 amino acid peptide produced primarily by endocrine cells of the ileal mucosa. Physiological actions of Neurotensin include hypertension, vasodilation, hyperglycemia, and inhibition of gastric motility. Its C-terminus is similar to Angiotensin I. It is a potent analgesic affecting hypothermia, muscle relaxation, and decreased motor activity. Pancreatic Polypeptide secretion is strongly stimulated by Neurotensin. Neurotensin appears to cause the release of Luteinizing Hormone-Releasing Hormone and Corticotropin Releasing Hormone effecting the release of Luteinizing Hormone, Follicle Stimulating Hormone, and ACTH but not Thyroid Stimulating Hormone or Growth Hormone. Neurotensin also stimulates pancreatic bicarbonate and intestinal secretion. Neurotensin levels are stimulated by food and Bombesin. Elevated levels have been found in pancreatic endocrine tumors, Oat Cell, Squamous Cell, and Adeno Carcinomas. Elevated levels have been found to cause watery diarrhea.

Reference Range

50 - 100 pg/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Collect specimen in "Z tube" (red top with preservative), available from MLabs, from a fasting patient (10-12 hour fast). Patient should not be on any antacid medication or medications that affect gastroentero-intestinal function, if possible, for at least 48 hours prior to collection. Following collection place Vacutainer® tube on ice, then centrifuge, aliquot plasma into a plastic vial, and freeze. If possible, discontinue insulin medication prior to collection.

Red Top Tube
Normal Volume
3 mL plasma
Minimum Volume
1 mL plasma

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.