Test Overview
Test Methodology


Test Usage

Assist in the diagnosis of dermatomyositis, polymyositis and the anti-synthetase syndrome as well as characterization of various subsets of these disorders and prognostic information.

Test Details
Analytic Time

14 - 21 days

Soft Order Code
  • Jo-1 Antibody
  • Mi-2 Antibody
  • PL-12 Antibody
  • PL-7 Antibody
  • EJ Antibody
  • OJ Antibody
  • SRP Antibody
  • Ku Antibody
  • U2 RNP Antibody
  • PM-Scl Antibody
  • MDA5 Antibody
  • NXP2 Antibody
  • TIF1 Antibody
  • SSA-52 kd IgG Antibody
  • U1 RNP Antibody
  • Fibrillarin U3 RNP Antibody
  • Myositis Specific Antibodies (MSA)
  • SAE-1 Antibody
Reference Laboratory
Labcorp (Esoterix # 520085)
Special Testing
Specimen Requirements

Collect specimen in an SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. EDTA plasma is also acceptable.

Special Handling

This test is restricted to Neurology and Rheumatology OUTPATIENTS only per Lab Formulary Committee. If requested by another service, they need to contact Dr Jeffrey Warren, Medical Director of Sendouts for permission. And the test will need to be ordered as a Miscellaneous Sendout in MiChart if approved.

Yellow Top Tube
Normal Volume
3 mL serum
Additional Information

Panel includes SAE-1, Jo-1, Mi-2, PL-12, PL-7, EJ, OJ, SRP, Ku, U2 RNP, PM-Scl, MDA5, NXP2, TIF1, SSA 52 kD IgG, U1 RNP, and Fibrillarin U3 RNP. Test sent to Labcorp Dublin; performed by Esoterix Endocrinology

CPT Code
83516 x9, 86235 x8
Fee Code
AA303 x9, AA305 x7, AA363
NY State Approved