Analytic Time

10 - 14 days

MiChart Code
Myomarker 3 Panel
Soft Order Code

Test Updated:


Jo-1 Antibody
Mi-2 Antibody
PL-12 Antibody
PL-7 Antibody
EJ Antibody
OJ Antibody
SRP Antibody
Ku Antibody
U2 RNP Antibody
PM-Scl Antibody
MDA5 Antibody
NXP2 Antibody
TIF1 Antibody
SSA-52 kd IgG Antibody
U1 RNP Antibody
Fibrillarin U3 RNP Antibody
Myositis Specific Antibodies (MSA)

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Test Overview

Test Methodology


Test Usage

The idiopathic inflammatory myopathies (IIM) are a heterogeneous group of disorders characterized by muscle weakness, resulting from chronic muscle inflammation of unknown cause. Patients with IIM have a variety of autoantibodies with various clinical utilities that fall into two main groups.
The first group is found only in patients with myositis and is known as Myositis Specific Autoantibodies (MSA). The MSAs have been shown to be highly specific for patients with polymyositis (PM), dermatomyositis (DM), anti-synthetase syndrome, necrotizing myositis and overlap syndromes.
The second group of antibodies is considered Myositis Associated Autoantibodies (MAA) and can be found in patients with overlap syndromes such as polymyositis/scleroderma. MAA can also be found in non-overlap syndromes.

Reference Range

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Yellow Top Tube
Normal Volume
3 mL serum
Minimum Volume

Billing Information

CPT Code
83516 x9, 86235 x7
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.