3 - 10 days
Test Updated:
LSI MYC t(8q;24) by FISH
FISH for Burkitt Lymphoma
MYCBAP
c-MYC (8q24) FISH
MLABEL
MCMYC
MYC (8q24) Rearrangement FISH
Looking to order a test?
We’ve provided helpful links to make ordering easy.
Find a RequisitionAll specimens should be accompanied by a requisition.
Submitting SpecimensLearn about how to properly label and where to ship specimens.
Order Kits and SuppliesMLabs provides all the supplies necessary for the collection of specimens.
Test FAQVisit our provider FAQ and learn about common questions to ordering tests.
Test Overview
Fluorescence In Situ Hybridization (FISH)
This test detects rearrangements involving the MYC gene region (8q24) via fluorescence in situ hybridization (FISH) in formalin-fixed, paraffin-embedded tissue specimens. FISH is performed using a dual color break apart probe (Abbott Molecular) to qualitatively assess for the presence of MYC translocations that occur in B-cell lymphomas. Testing for MYC gene rearrangement may aid in the diagnosis of Burkitt lymphoma, and may indicate an aggressive clinical course in other B-cell lymphomas.
Interpretive report provided.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Specimen Requirements
A formalin-fixed, paraffin-embedded tissue block containing sufficient neoplastic cells is preferred. Unstained slides (3, 4-micron slides) with associated H&E stained slide are also acceptable. Decalcified tissue or other fixatives will be accepted and the assay attempted, however these may result in failed testing due to degraded nucleic acid. Both blocks and slides should be stored at room temperature.