Update Type: Test Down or Delayed
Test Updated: 01/19/2022
Test Overview
Test Methodology

Flow Cytometry; multi-fluorochrome

Test Usage

This test is for evaluating the depth of response after treatment for multiple myeloma

Reference Range *

Pathologist interpretation of results provided.

*Reference ranges may change over time. Please refer to the original patient report when evaluating results.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Requires an adequate number of viable cells for analysis. When sample volume is 4 ml or less, immunophenotypic analysis may not be successful.

Test Details
Days Set Up
Monday-Saturday, 7am-3pm
Analytic Time

8-48 hours

Soft Order Code
MiChart Code
Minimal Residual Disease for Multiple Myeloma, Flow Cytometry
Flow Cytometry
Flow Cytometry
Specimen Requirements

Should be collected from a first pull aspirate (the person collecting the marrow should redirect the Jamshidi) into a heparinized syringe that will be transferred into a 7ml green top and thoroughly mixed

Collection Instructions

The following information is required on a Hematopathology Consult requisition:

1.Relevant clinical history
2.Clinical or morphological findings and suspicions
3.Specimen source
4.Date and time of collection
5.Phone number and after hours pager number for ordering physician

Add 4 ml of first pull bone marrow aspirate to a green top sodium heparin Vacutainer® tube. Send intact specimen at room temperature within 12 hours of collection.

Special Handling

Samples received in heparin at room temperature.
Sample should be less than 48 hours old when set up.
Specimens may be processed after 48 hours and will be processed up to 72 hours and reported with a comment regarding specimen age.

This test should not be used for a new diagnosis of plasma cell neoplasm or for relapsed/refractory disease, please order Leukemia/Lymphoma Immunophenotyping instead, and include history
Normal Volume
4 ml
Minimum Volume
2 ml
Storage Temperature
Samples received in heparin at room temperature.
Rejection Criteria
Green top with lithium heparin is unacceptable.
Additional Information

Test includes pathologist interpretation of results billed as a separate additional charge. This test is not available without interpretation. Additonal markers will be run if clinically indicated. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. For consultation contact the MLabs Client Services Center or Flow Cytometry Laboratory at 763-9420.

CPT Code
88184, 88185 x10, 88188