Test Overview
The Mid Gastrointestinal Panel (MIDGI) is a multiplexed nucleic acid test intended for qualitative detection of multiple gastrointestinal bacteria, viruses and parasites. This test is intended for use in patients with diarrhea that began prior to or within three days of hospitalization and there is concern for other etiologies aside from C. difficile. The MIDGI should not be used as the primary test for the detection of C. difficile infection. If indicated, order PCRCD test code.
Not detected
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Specimens that are positive for the C. difficile toxin A/B gene by FilmArray Mid Gastrointestinal Panel are immediately reflexed to a C. difficile Toxin A/B EIA assay to assess the specimen for the presence of detectable levels of Toxin A or B. Consult pediatric ID for assistance on interpretation of positive results for C. difficile in children <1 year of age.
This test does not detect Aeromonas spp or Plesiomonas spp. Call laboratory if culture for this organism is indicated.
Target genes associated with the diarrheagenic E. coli/Shigella pathotypes are capable of horizontal transfer between strains, thus detected results for multiple diarrheagenic E.coli/Shigella may be due to co-infection with multiple pathotypes or, less frequently, may be due to the presence of a single organism containing genes characteristic of multiple pathotypes.
Shigella dysenteriae possess a shiga toxin gene (stx) that is identical to the stx1 gene of STEC. The detection of both Shigella/Enteroinvasive E. coli (EIEC) and STEC stx1/stx2 analytes in the same specimen may indicate the presence of S. dysenteriae.
Test Details
- Clostridium difficile toxin A/B
- Campylobacter
- Giardia lamblia
- Norovirus GI/GII
- Salmonella
- Vibrio
- Cyclospora cayetanensis
- Cryptosporidium
- Shigella/Enteroinvasive E.coli (EIEC)
- MIDGI
- MID GI Panel
- Vibrio
- Yersinia enterocolitica
- Shiga-like toxin-producing E.coli(STEC)
Specimen Requirements
Collect fresh random stool specimen. Transfer fresh stool specimen to Cary Blair transport within 2 hours from collection if held at room temp or within 24 hours if held refrigerated. Fill transport until liquid reaches fill line. Emulsify specimen thoroughly in transport fluid. If necessary, place a urine bag on the patient to prevent urine contamination. Acceptable specimens are stool sent in Stool Culture transport (orange cap - Cary Blair) stored at room temperature or refrigerated for up to 4 days. If an unacceptable specimen is received, the client will be notified before disposal of the original specimen. See MLabs Stool Specimen Collection Instructions available online at https://mlabs.umich.edu/media/175 for patient instructions.
5 grams of stool
Additional Information
Panel includes: Campylobacter, Clostridium difficile toxin A/B, Salmonella, Vibrio, Yersinia enterocolitica, Shiga-like toxin-producing E.coli (STEC), Shigella/Enteroinvasive E.coli (EIEC), Cryptosporidium, Cyclospora cayetanensis, Giardia lamblia, and Norovirus GI/GII.
For guidance on use of the GI panel, please copy and paste the following link into a new browser window:
https://www.pathology.med.umich.edu/static/apps/cms/ckfinder/userfiles/…