Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Monitor therapeutic drug level
Therapeutic: 0.5 - 2.0 mcg/mL; Toxic: greater than 2 mcg/mL.
2 - 6 days
Collect a trough specimen in a red top tube after patient has been receiving Mexiletine for at least 3 days; do not use SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.
Test sent to Mayo Clinic Laboratories.