Test Overview
PCR
The MRSA screen PCR assay is an automated qualitative in vitro diagnostic nucleic acid amplification test for the direct detection of methicillin-resistant Staphylococcus aureus (MRSA) DNA from nasal swabs in patients at risk for colonization. Active surveillance using molecular tests for rapid detection of MRSA is a proven strategy to reduce transmission in healthcare settings and prevent infection in vulnerable patients. Early identification of patients with MRSA nasal carriage can be part of an effective infection prevention program for MRSA.
Approximately 5% of patients in U.S. hospitals carry MRSA in their nose or on their skin. MRSA can cause severe problems including bacteremia, pneumonia, or surgical site infections. Nasal decolonization has been shown to decrease rates of MRSA infection for admitted patients.
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No MRSA DNA detected
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Screening determines the colonization status at a given time. Colonization may vary depending upon patient treatment (e.g., decolonization regime), patient status (e.g., transient MRSA colonization) or exposure to high-risk environments (e.g., contact with MRSA carrier and/or prolonged hospitalization). Colonization status should be monitored according to institutional policies.
Test Details
Specimen Requirements
Nasal specimens should be collected according to the following:
1. Moisten the swab(s) with two drops (approximately 50 μL) of sterile physiological saline or use dry.
2. Carefully insert the swab(s) into the patient’s nostril (a swab tip should be inserted up to 2.5 cm [1 inch] from the edge of the nares).
3. Roll the swab(s) along the mucosa inside the nostril 5 times.
4. Insert the same swab(s) into the second nostril and repeat steps 2 and 3.
5. Place the swab(s) in its transport tube.
Refrigerated: Up to 5 days
Incorrect transport media