Test Overview
Test Methodology

Enzymatic Immunoassay

Test Usage

This test is for the qualitative detection of methadone metabolite (2-ethylene-1,5-dimethyl-3,3-diphenylpyrrolidine or EDDP) in urine at a cutoff concentration of 100 ng/mL.

Reference Range *

Negative

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Daily, 24 hrs
Analytic Time

1 hour

Soft Order Code
UMETM
MiChart Code
Methadone Metabolites, Urine
Synonyms
  • UMETHM
  • Methadone Metabolite, Urine
  • 2-ethylene-1,5-dimethyl-3-3-diphenylpyrrolidine
  • EDDP
  • EDDP
  • METHADONE, URINE SCREEN
  • UMETHAD
  • METHG
  • METHADONE CONFIRM W/C.O.C.
Laboratory
Chemical Pathology
Section
Automation
Specimen Requirements
Collection Instructions

Collect random urine specimen. Refrigerate

Normal Volume
5 mL urine
Minimum Volume
1 mL urine
Additional Information

Methadone is a synthetic opiate commonly used to detoxify and maintain heroin addicts. Methadone treatment compliance can be effectively monitored by urine screening of methadone and its metabolite. Methadone is quickly metabolized by the liver into normethadone which is hard to detect due to its rapid dehydration to EDDP (primary metabolite) If methadone testing only is performed, only the parent drug is being measured leading to possible false positive (urine adulteration by the addict) or negative (only metabolite present in high enough quantity to measure) results. EDDP Qualitative Confirmation (UMETM) performed by Drug Analysis and Automation Laboratory. Quantitative Confirmation (SO) sent to Warde Medical Laboratory (includes methadone and EDDP).

Billing
CPT Code
80307
Fee Code
21628
LOINC
77752-4
Resources