Test Overview
Test Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Test Usage

Therapeutic Drug Monitoring

Test Limitations

Methadone has a wide therapeutic index and dose-dependent toxicity. As a result, routine drug monitoring is not indicated in all patients.

Test Details
Days Set Up
Tuesday, Thursday, Sunday
Analytic Time

4 - 6 days

Soft Order Code
MDNS
MiChart Code
Methadone, Serum (Sendout)
Synonyms
  • MTDNS
  • Methadone, Serum
  • MDNS
Laboratory
Sendout
Reference Laboratory
Mayo MDNS
Section
Special Testing
Specimen Requirements
Collection

SST not acceptable

Collection Instructions

Collect specimen in a red top tube (no SST). Centrifuge within 2 hours, aliquot serum into a plastic vial and refrigerate.

Normal Volume
0.5 mL serum
Additional Information

Test sent to Mayo Medical Laboratories.

Billing
CPT Code
80358
Fee Code
22016
NY State Approved
No