Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Therapeutic Drug Monitoring
Methadone has a wide therapeutic index and dose-dependent toxicity. As a result, routine drug monitoring is not indicated in all patients.
4 - 6 days
- Methadone, Serum
SST not acceptable
Collect specimen in a red top tube (no SST). Centrifuge within 2 hours, aliquot serum into a plastic vial and refrigerate.
Test sent to Mayo Medical Laboratories.