Test Overview
Test Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Test Usage

Therapeutic Drug Monitoring

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Methadone has a wide therapeutic index and dose-dependent toxicity. As a result, routine drug monitoring is not indicated in all patients.

Test Details
Days Set Up
Monday - Thursday, Sunday
Analytic Time

2 - 4 days

Soft Order Code
MDNS
MiChart Code
Methadone, Serum (Sendout)
Synonyms
  • MTDNS
  • Methadone, Serum
  • MDNS
Laboratory
Sendout
Reference Laboratory
Mayo MDNS
Section
Special Testing
Specimen Requirements
Collection

SST not acceptable

Collection Instructions

Collect specimen in a red top tube (no SST). Centrifuge within 2 hours, aliquot serum into a plastic vial and refrigerate.

Yellow Top Tube
Normal Volume
0.5 mL serum
Additional Information

Test sent to Mayo Medical Laboratories.

Billing
CPT Code
80358
Fee Code
22016
NY State Approved
No
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