Test Overview
Test Methodology

Metagenomic Next-Generation Sequencing (NGS)

Test Usage

This test detects and identifies bacteria, DNA and RNA viruses, fungi, and parasites in cerebrospinal fluid using next generation sequencing.

Reference Range *

Negative
No pathogenic DNA virus detected.
No pathogenic RNA virus detected.
No pathogenic parasite detected.
No pathogenic bacterium detected.
No pathogenic fungus detected.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday
Analytic Time

7 - 14 days

Soft Order Code
MSCSF
Synonyms
  • mNGS
Laboratory
Sendout
Reference Laboratory
Mayo MSCSF
Section
Special Testing
Specimen Requirements
Collection Instructions

Aliquot CSF from 2, 3 or 4 (NO tube 1 aliquots) into a sterile screw capped plastic tube. Send to Specimen Processing frozen. Indicate on the aliquot label which tube was used to make the aliquot.

Special Handling

Do not use tube #1 to make the aliquot. Do not use centrifuged or heat inactivated specimens

This test requires approval from the Michigan Medicine Pathology Microbiology leadership- either the current resident or one of the PhD Directors.

Normal Volume
2 mL CSF
Minimum Volume
0.5 mL CSF
Storage Temperature
Frozen preferred, refrigerated acceptable
Additional Information

Test performed by Mayo Clinic Laboratories

Billing
CPT Code
87801, 87798