Polymerase chain reaction (PCR)
Thr FilmArray Meningitis/Encephalitis (ME) Panel is capable of simultaneous detection and identification of multiple bacterial, viral, and yeast nucleic acids directly from cerebrospinal fluid (CSF) specimens obtained via lumbar puncture from individuals with signs and/or symptoms of meningitis and/or encephalitis. The following organisms are identified using the FilmArray ME Panel:
Escherichia coli K1
Neisseria meningitidis (encapsulated)
Herpes simplex virus 1
Herpes simplex virus 2
Human herpesvirus 6
Varicella zoster virus
The FilmArray ME Panel is indicated as an aid in the diagnosis of specific agents of meningitis and/or encephalitis and results are meant to be used in conjunction with other clinical, epidemiological, and laboratory data. Results are not intended to be used as the sole basis for diagnosis, treatment, or other patient management decisions. Positive results do not rule out co-infection with organisms not included in the FilmArray ME Panel. The agent detected may not be the definite cause of the disease. Negative results do not preclude central nervous system (CNS) infection. The FilmArray ME Panel is not intended for testing of specimens collected from indwelling CNS medical devices.
CSF specimens should be collected via lumbar puncture, and should not be centrifuged.