Anti-MDA5 antibodies are present in 7-35% of adult DM. Features consist of absent or mild muscle symptoms (CADM); associated with rapidly progressive ILD; specific mucocutaneous features of skin ulcerations and papules; higher risk of oral ulcerations and arthritis.
- MDA-5 (P140) (CADM-140)
Collect specimen in an SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.
Test sent to Labcorp Dublin; performed by Esoterix Endocrinology