Test Overview
ELISA
To help in the diagnosis of biliary atresia
3.6 - 10.5 ng/mL
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
MMP-7 level ≥ 18.2 ng/mL has 95% sensitivity and 65% specificity for diagnosis of biliary atresia, with negative predictive value of 97%.
Caution should be exercised in the interpretation of any assay for MMP-7, and the results should be considered in conjunction with the patient’s clinical condition. High MMP-7 have been detected in premature babies and young infants with cardiovascular and/ or multi-system disease. The final diagnosis of biliary atresia requires intraoperative cholangiography and the histological presence of obstruction of the extrahepatic bile duct. The normal values of MMP-7 in premature babies have not yet been established. Clinical correlation is particularly important in premature babies.
Test Details
3 - 4 days
Specimen Requirements
Collect specimen in SST or red top tube. Place specimen on ice immediately after collection. Spin, aliquot and freeze within 2 hours of collection. Ship to Dallas Monday-Thursday only. Store frozen over the weekend if one is received on a Friday in sendouts
Place on ice immediately after collection. Spin, aliquot and freeze within 2 hours of collection
Ship Monday - Thursday only. Lab is not open on weekends. Store frozen if one is received on a Friday in Sendouts
Additional Information
Test is performed by Children's Medical Center of Dallas