Test Overview
Test Methodology

Liquid Chromatography/Mass Spectrometry (LC/MS)

Test Usage

Therapeutic Monitoring, Assessing Compliance

Reference Range *

The proposed therapeutic range for control of seizures is 3.0 - 14.0 mcg/mL. Drug pharmacokinetics varies widely, being especially affected by decreased renal function and co-medications.

Test Details
Days Set Up
Wednesday, Friday
Analytic Time

8 hours

Soft Order Code
LAMOT
MiChart Code
Lamotrigine Level
Synonyms
  • Lamictal
  • LAMOT
  • LAMOTRIGINE
  • LAMOTRIGINE LEVEL
Laboratory
Chemical Pathology
Section
Drug Analysis
Specimen Requirements
Collection Instructions

Collect specimen in a red top tube; do not use SST tube. A lavender (EDTA) or green top (Heparin) tube is also acceptable. Centrifuge, aliquot serum or plasma into a plastic vial, and refrigerate.

Normal Volume
1 mL serum or plasma
Minimum Volume
0.3 mL serum or plasma
Rejection Criteria
SST tube not acceptable.
Additional Information

Lamotrigine is an antiepileptic drug that has been shown to be effective as add-on therapy for patients with resistant partial seizures. The drug may also be effective in treating generalized tonic-clonic seizures, some cases of Lennox-Gestaut syndrome, and in children with multiple seizure types.

Billing
CPT Code
80175
Fee Code
20534
LOINC
6948-4
NY State Approved
No