Test Overview
Test Methodology

Liquid Chromatography/Mass Spectrometry (LC/MS)

Test Usage

Therapeutic Monitoring, Assessing Compliance

Reference Range *

The proposed therapeutic range for control of seizures is 3.0 - 14.0 mcg/mL. Drug pharmacokinetics varies widely, being especially affected by decreased renal function and co-medications.

Test Details
Days Set Up
Wednesday, Friday
Analytic Time

8 hours

Soft Order Code
LAMOT
MiChart Code
Lamotrigine Level
Synonyms
  • Lamictal
  • LAMOT
  • LAMOTRIGINE
  • LAMOTRIGINE LEVEL
Laboratory
Chemical Pathology
Section
Drug Analysis
Specimen Requirements
Collection Instructions

Collect specimen in a red top tube; do not use SST tube. A lavender (EDTA) or green top (Heparin) tube is also acceptable. Centrifuge, aliquot serum or plasma into a plastic vial, and refrigerate.

Rejection Criteria
SST tube not acceptable.
Yellow Top Tube
Red Top Tube
Normal Volume
1 mL serum or plasma
Minimum Volume
0.3 mL serum or plasma
Additional Information

Lamotrigine is an antiepileptic drug that has been shown to be effective as add-on therapy for patients with resistant partial seizures. The drug may also be effective in treating generalized tonic-clonic seizures, some cases of Lennox-Gestaut syndrome, and in children with multiple seizure types.

Billing
CPT Code
80175
Fee Code
20534
LOINC
6948-4
NY State Approved
No