Update Type: Test Code Change
Test Updated: 11/16/2022
Test Overview
Test Methodology

Polymerase Chain Reaction (PCR)

Test Usage

Monitoring of viral load to track the course of infection and response to treatment.

Test Details
Days Set Up
Monday - Saturday
Analytic Time

1 day

Soft Order Code
MiChart Code
JCV DNA by PCR, Blood
  • JCV DNA qPCR, Blood
Reference Laboratory
Viracor Eurofins 3500
Special Testing
Specimen Requirements

Collect specimen in a lavender top (EDTA) tube. Centrifuge and aliquot plasma into a plastic vial. Store and transport at room temperature.

Alternate Specimen
Acceptable specimen types (1/23/12): CSF, plasma, serum, urine.
Normal Volume
2 mL EDTA plasma
Minimum Volume
2 mL EDTA plasma
Additional Information

JCV virus establishes latency in the kidney and virus is shed sporadically through life and more frequently during pregnancy or immunosuppression. JC virus causes progressive multifocal leukoencephalopathy (PML), which is a subacute demyelinating disease of the CNS and is seen mainly in advanced disseminated malignant conditions, immunodeficiency syndromes, and in immunosrppressed patients following organ transplantation. The disease PML represents a reactivation of longstanding persistent infection of the kidney and perhaps also of the brain. JC virus has also been associated with hemorrhagic cystitis, ureteral stenosis and allograft dysfunction. Test sent to Viracor Eurofins.

CPT Code
Fee Code