Days Set Up
Monday through Friday
Analytic Time

1 - 3 days

MiChart Code
Itraconazole Level
Soft Order Code

Test Updated:


Itraconazole, S/P

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Test Overview

Test Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Test Usage

Verifying systemic absorption of orally administered itraconazole. This test is indicated in patients with life-threatening fungal infections and in patients considered at risk for poor absorption or rapid clearance.

Reference Range

Itraconazole (trough): >0.5 mcg/mL (localized infection); >1.0 mcg/mL (systemic infection). Hydroxyitraconazole: No therapeutic range established; activity and serum concentration are similar to parent drug.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Collect specimen in a red top tube; do not use SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. For maximum clinical significance, usual sampling times are Peak: 30 minutes after the end of an I.V. infusion (60 minutes after I.M. or oral administration) or Trough: immediately before next dose is given.

Yellow Top Tube
Red Top Tube
Normal Volume
1 mL serum
Minimum Volume
0.2 mL serum

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.