High-Performance Liquid chromatography with Ultraviolet Detection (HPLC-UV)
Therapeutic Drug Monitoring
The effective concentration range of isoniazid is dependent upon the minimum inhibitory concentration of the pathogen being treated. Toxic range: greater than 20 ug/mL.
Isoniazid is known to have limited stability in biological specimens which may be concentration and storage condition dependent. Negative or lower than expected results should be interpreted with caution.
5 - 9 days
Collect specimen in a red top tube; do not use SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate (preferred) or freeze.
Test sent to Mayo Medical Laboratories; performed by MedTox Laboratories.