Test Overview
Test Methodology

Dynamic Reaction Cell-Inductively Coupled Plasma/Mass Spectrometry (DRC-ICP/MS)

Test Usage

Definitive diagnosis of hemochromatosis.

Reference Range *

IRON: Male: 200 - 2,400 mcg/g dry weight, Female: 200 - 1800 mcg/g dry weight. IRON INDEX: <1.0 mcmol/g/year. Reference values have not been established for patients less than 13 years of age.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday, Wednesday, Friday
Analytic Time

2 - 6 days

Soft Order Code
FE-T
MiChart Code
Iron, Liver Tissue (Sendout)
Synonyms
  • Hemochromatosis
  • Hepatic Iron Concentration
  • Liver Tissue, Fe
Laboratory
Sendout
Reference Laboratory
Mayo FET (8350)
Section
Special Testing
Specimen Requirements
Collection Instructions

A minimum of 2 mg of fresh or frozen liver tissue is required for analysis. This is typically a piece of tissue from a 14-gauge needle biopsy at least 0.5 cm long. If an 18-gauge needle is used, the tissue must be at least 1 cm in length. The 18-gauge needle produces a specimen that is thin and fragile and difficult to handle. Fresh or frozen specimen is preferred. Place specimen in a metal free container and refrigerate.

Alternate Specimen
Paraffin block is acceptable if not more than 1 or 2 cuts have been made to it for slides. Formalin-fixed, paraffin-embedded tissue can be used when histologic examination including iron stains are requested, in addition to the hepatic iron concentration and calculated HII. However, fresh or frozen tissue is preferred.
Contraindications
Do not collect specimens from patients who have received gadolinium within the past 48 hours. Gadolinium, a material contained in some contrast media, is known to interfere with most metals tests.
Normal Volume

2 mg fresh or frozen liver tissue

Minimum Volume

2 mg fresh or frozen liver tissue

Additional Information

Test sent to Mayo Medical Laboratories.

Billing
CPT Code
83540
Fee Code
22011
NY State Approved
No