Test Overview
IGFBP-3: Enzyme-Labeled Chemiluminescent Immunometric Assay, IGF-1: Liquid Chromatography-Mass Spectrometry (LC-MS).
In combination with IGF-1 measurements, IGFBP-3 measurements are useful for the diagnosis of growth disorders, the diagnosis of adult GH-deficiency, monitoring of rhGH treatment, and as a possible adjunct to IGF-1 and GH in the diagnosis and follow-up of acromegaly and gigantism. At this time, IGFBP-3 cannot be reliably used as a prognostic marker in breast, colon, prostate or lung cancer.
Age specific ranges provided with report.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
IGF-1 assays exhibit significant variability among platforms and manufacturers. Direct comparison of results obtained by different assays is problematic. Re-baselining of patients is recommended if assays are changed.
Test Details
5 - 9 days
- Insulin-Like Growth Factor Growth Assessment Group
- Growth Assessment Group V
- IGF-1 and IGFBP-3
Specimen Requirements
Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into two equal portions, and freeze.
Additional Information
Test includes Insulin-Like Growth Factor Binding Protein (IGFBP-3) and Insulin-Like Growth Factor (IGF-1). Test sent to Mayo Medical Laboratories.