Test Overview
Test Methodology

Enzyme-Labeled Chemiluminescent Immunometric Assay

Test Usage

In combination with IGF-1 measurements, IGFBP-3 measurements are useful for the diagnosis of growth disorders, the diagnosis of adult GH-deficiency, monitoring of rhGH treatment, and as a possible adjunct to IGF-1 and GH in the diagnosis and follow-up of acromegaly and gigantism. At this time, IGFBP-3 cannot be reliably used as a prognostic marker in breast, colon, prostate or lung cancer.

Reference Range *

Age specific ranges provided with report.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

IGFBP-3 assays exhibit significant variability among platforms and manufacturers. Direct comparison of results obtained by different assays is problematic. Re-baselining of patients is recommended if assays are changed.

Test Details
Days Set Up
Monday - Friday
Analytic Time

1 - 3 days

Soft Order Code
MiChart Code
Insulin-Like Growth Factor Binding Protein
  • IGF Binding Protein
  • IGFBP-3
  • IGFBP3
  • IGF Binding Protein-3, Serum
Reference Laboratory
Mayo IGFB3 (83300)
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and freeze.

Normal Volume
0.8 mL serum
Minimum Volume
0.3 mL serum
Additional Information

Test sent to Mayo Medical Laboratories.

CPT Code
Fee Code