Update Type: Specimen collection or handling and/or storage changed
Test Updated: 12/06/2023
Test Overview
Test Methodology

Selective Reaction Monitoring LC-MS/MS; Electrochemiluminescent Bridging Immunoassay

Test Usage

Trough level quantitation for evaluation of patients with loss of response to infliximab.

Reference Range *

Therapeutic concentrations of infliximab may vary according to the disease.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
INFX: Monday, Wednesday, Thursday
INXAB: Monday, Wednesday, Friday
Analytic Time

4 - 10 days

Soft Order Code
INFXR
MiChart Code
Infliximab and Anti-Infliximab Ab
Synonyms
  • FIAIA
  • Infliximab Concentration and Anti-Infliximab Antibody
  • Remicade
  • Anser IFX Equivalent
  • INFXR
  • INXAB
Laboratory
Sendout
Reference Laboratory
Mayo INFXR
Section
Special Testing
Specimen Requirements
Collection

Collect specimen in a red top tube; do not use an SST tube. Centrifuge, aliquot serum into a plastic vial, and refrigerate within 2 hours of collection.

Collection Instructions

Collect specimen in a red top tube (SST unacceptable) immediately before the next dose of Infliximab. Spin and aliquot into a screw capped plastic tube within 2 hours of collection. Send to Specimen Processing refrigerated.

Normal Volume
1 mL serum
Minimum Volume
0.5 mL serum
Storage Temperature
Refrigerated preferred, frozen acceptable.
Rejection Criteria
SST tube not acceptable.
Additional Information

Test includes infliximab quantitation by LC-MS/MS. If infliximab concentration is <5.1 mcg/mL, infliximab antibodies (INXAB) will be performed at an additional charge. (Will be ordered by the interface IF needed, do not order in Soft) By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Test sent to Mayo Medical Laboratories.

Billing
CPT Code
80230
Fee Code
AA690
Reflex CPT
82397
Reflex Fee Code
AA384