Update Type: Replacement Test
Test Updated: 07/21/2021
Test Overview
Test Methodology

AASCA, GASCA: Enzyme-Linked Immunosorbent Assay (ELISA)
NSA: Indirect Immunofluorescent Assay (IFA)

Test Usage

As an adjunct in the diagnosis of ulcerative colitis and Crohn disease in patients suspected of having inflammatory bowel disease

Reference Range *

Saccharomyces cerevisiae ANTIBODY, IgA or IgG
Negative: < or =20.0 U; Equivocal: 20.1-24.9 U; Weakly positive: 25.0-34.9 U; Positive: > or =35.0 U

Neutrophil specific antibodies: Negative (not detected)

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Not useful to determine the extent of disease in patients with inflammatory bowel disease (IBD) or determine the response to disease-specific therapy including surgical resection of diseased intestine

Test Details
Days Set Up
Analytic Time

2 - 10 days

Soft Order Code
  • IBD
Reference Laboratory
Mayo IBDP2
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in an SST or red top tube. Spin, aliquot into a screw capped plastic tube and send to Specimen Processing refrigerated.

Normal Volume
1 mL serum
Minimum Volume
0.8 mL serum
Storage Temperature
Frozen acceptable
Additional Information

Test performed by Mayo Clinic Laboratories

CPT Code
86036, 86671 x2
Fee Code
AA989, AA510, AA511