Days Set Up
Monday - Friday, 8:00am - 4:30pm; Saturday 8:00am-12:00noon
Analytic Time

8 - 48 hrs

MiChart Code
Leukemia/Lymphoma Immunophenotyping; Non-Blood, Flow Cytometry
Soft Order Code
LEUKS

Test Updated:

Synonyms

B and T Cell Typing for Lymphocytic Leukemias
Leukemia / Lymphoma Immunophenotyping
Lymphocyte Typing for Lymphoproliferative Disorders
Lymphocytic Leukemias, Acute and Chronic Subtyping
T and B Cell Typing for Lymphocytic Leukemias
Leukemias, Acute
Leukemias, Chronic
Chronic Lymphocytic Leukemia (CLL)
Mixed Linage Acute Leukemia
Acute Lymphocytic Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Leukemia/Lymphoma, Uncertain Subtype
Plasma Cell Panel (PCL)
ACUTE
NONACUTE
LEUKS
ACUTE MARKER PANEL
NONACUTE MARKER PANEL
COMBO
Leukemia/Lymphoma Workup
Prolymphocytic Leukemia (PLL)
Mantle Cell Lymphoma/Leukemia (MCL)
Hairy Cell Leukemia (HCL)
Non-Hodgkin's Lymphoma
Follicular Lymphoma
Diffuse Large B-Cell Lymphoma (DLBCL)
Leukemia/Lymphoma Acute Marker Panel
Leukemia/Lymphoma Nonacute Marker Panel
Leukemia/Lymphoma Combo Marker Panel
Panel 3: Plasma Cell / Multiple Myeloma
Panel 1: Stem Cell Neoplasm / Acute Leukemia
Panel 2: Mature Lymphoid Leukemia / Non-Hodgkin Lymphoma
Panel 4: Comprehensive Leukemia / Lymphoma
Multiple Myeloma

Looking to order a test?

We’ve provided helpful links to make ordering easy.

Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

Learn about how to properly label and where to ship specimens.

Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

Test FAQ

Visit our provider FAQ and learn about common questions to ordering tests.

Test Overview

Test Methodology

Direct immunofluorescence using flow cytometric techniques.

Test Usage

Confirmation of diagnosis and immunophenotype in acute and chronic leukemias and lymphomas. See http://www.pathology.med.umich.edu/handbook/Tables/Flow_Cytometry_Panel… for all Flow Cytometry Panels.

Reference Range

Pathologist interpretation of results provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

The following information is required on a Hematopathology Consult requisition:
[list order=Y]
Relevant clinical history
Clinical or morphological findings and suspicions
Specimen source
Date and time of collection
Phone number and after hours pager number for ordering physician
[/list]

[bold]BONE MARROW ASPIRATE:[/bold]
[list]
Add 1 - 2 ml of first pull bone marrow aspirate to a green top sodium heparin Vacutainer® tube. Send intact specimen at room temperature within 12 hours of collection.
Include 4 unstained aspirate smears
Include an unstained peripheral blood smear
Include a copy of the patient's most recent White Blood Cell and platelet counts, and peripheral blood differential.
[/list]
[bold]BODY FLUID and CSF:[/bold]
[list]
Add body fluid (e.g., CSF, pleural, peritoneal) to a clean, leak proof sterile container and send at room temperature within 12 hours of collection.
Include a a copy of the body fluid cell count and differential.
An original cytospin preparation (preferably unstained) should be included when possible with CSF specimens for correlative morphological evaluation.
[/list]
[bold]BONE MARROW CORE BIOPSY AND FNA:[/bold]
[list]
Submerge in RPMI tissue culture medium (for optimal cell viability) or sterile saline and transport at room temperature within 12 hours of collection.
[/list]
[bold]FRESH TISSUE:[/bold]
[list]
Mince and submerge in RPMI tissue culture medium (for optimal cell viability) or sterile saline, refrigerate, and transport refrigerated within 12 hours of collection.
[/list]

Red Top Tube
Normal Volume
[list]
[bold]BONE MARROW ASPIRATE:[/bold] 1-2 ml
[bold]BODY FLUIDS:[/bold] 20-50 ml
[bold]CSF:[/bold] 5-10 ml
[/list]
Minimum Volume
[list]
[bold]BONE MARROW ASPIRATE:[/bold] 1 ml
[bold]BODY FLUIDS:[/bold] 10 ml*
[bold]CSF:[/bold] 1 ml*
[/list]
* The volume of Body Fluids and CSF required is dependent on the cellularity of the specimen.

Billing Information

CPT Code
ACUTE: 88184, 88185 x23, 88189; NONACUTE: 88184, 88185 x13, 88188; COMBO: 88184, 88185 x22, 88189, PCL: 88184, 88185 x8, 88188
Pro Fee Code
ACUTE: 88189.1, NONACUTE: 88188.3, COMBO: 88189.2
LOINC
Z501-7

Have More Questions?

Explore our helpful billing resources:

Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.