Test Overview
Test Methodology

Nephelometry

Test Usage

To evaluate humoral immunity, monitor therapy in myeloma. To evaluate malabsorption syndrome, giardiasis, and lactase deficiency. IgA deficiencies are associated with a high incidence of autoimmune disease. Isolated IgA deficiency is usually associated with chronic respiratory infections and allergies. IgA may be elevated in any disease affecting mucosal surfaces. IgA and IgE may be low in ataxia telangiectasia.

Reference Range *

Cord blood (age <1 mos): 1 - 4 mg/dL, age 1 mos: 2 - 50 mg/dL, age 2-9 mos: 4 - 80 mg/dL, age 10-11 mos: 15 - 90 mg/dL, age 1-4 yrs: 15 - 160 mg/dL, age 5-11 yrs: 35 - 250 mg/dL, age 12-150 yrs: 40 - 350 mg/dL.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

If samples containing macroglobulins, cryoglobulins or cold agglutinins are handled at incorrect temperatures falsely lowered values may result.

Test Details
Days Set Up
Monday - Friday
Analytic Time

8 hours

Soft Order Code
IGA
MiChart Code
IgA
Synonyms
  • IgA
  • Quantitative IgA
  • IMMUNOGLOBULIN A
Laboratory
Chemical Pathology
Section
Immunopathology
Specimen Requirements
Collection Instructions

Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. Store at 2-8°C up to 8 days.
Samples may be frozen at -20°C or below for up to 3 months if they are frozen within 24 hours after collection.

Alternate Specimen
Red top
Yellow Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.3 mL serum
Additional Information

IgA is the principal secretory antibody along mucous membrane surfaces. IgA is commonly increased in respiratory and GI infections, IgA myeloma, malabsorption or malnutrition, diarrhea, metastatic liver tumors, and some autoimmune diseases (e.g., SLE). Deficient and, rarely, absent serum IgA globulin occurs in some clinically asymptomatic individuals.

Billing
CPT Code
82784
Fee Code
21986
Resources