Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Evaluation of suspected insulinoma characterized by hypoglycemia and increased plasma insulin concentration. Detecting drugs that stimulate insulin secretion.
Negative. Threshold cut off levels: Acetohexamide 1000 ng/mL; Chlorpropamide 1000 ng/mL; Tolazamide 20 ng/mL; Tolbutamide 50 ng/mL; Glimepiride 20 ng/mL; Glipizide 3 ng/mL; Glyburide 3 ng/mL; Repaglinide 3 ng/mL.
Proper interpretation requires that the blood specimen be drawn during or close to the time of a hypoglycemic episode. Drugs will not be detected (and are not likely to be present) if blood is drawn when blood glucose is normal in nondiabetic patients. This test is not intended for therapeutic drug monitoring.
2 - 8 days
- Sulfonylurea Hypoglycemic Serum
- Hypoglycemic Agent Scrn, S
Collect specimen in a red top tube; do not use SST tube. Centrifuge, aliquot serum into a plastic vial and freeze.
Test sent to Mayo Medical Laboratories.