Test Overview
Test Methodology


Test Usage

The presence of human anti-mouse antibody (HAMA) has been associated with patients receiving injections of murine monoclonal antibody (MAb) for diagnostics and/or theraputic purposes. HAMA produced in response to monoclonal antibody therapy may interfere with theraputic efficacy. Therefore, it is recommended that baseline HAMA levels are determined prior to the initiation of therapy with murine-derived proteins.

Reference Range *

<74 ng/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

HAMA may be detected in a small percentage of the general population, and usually represent heterophilic antibodies or dietary exposure to murine proteins.

Test Details
Days Set Up
Analytic Time

7 - 15 days

Soft Order Code
  • HAMA
Reference Laboratory
Quest Valencia 1468
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in a red top tube. Centrifuge, aliquot serum into a plastic vial and freeze.

Normal Volume
1 mL serum
Minimum Volume
0.5 mL serum
Rejection Criteria
SST is not acceptable
Additional Information

Quest Diagnostics Nichols Institute of Valencia.

CPT Code