Test Overview
Test Methodology
ELISA
Test Usage
The presence of human anti-mouse antibody (HAMA) has been associated with patients receiving injections of murine monoclonal antibody (MAb) for diagnostics and/or theraputic purposes. HAMA produced in response to monoclonal antibody therapy may interfere with theraputic efficacy. Therefore, it is recommended that baseline HAMA levels are determined prior to the initiation of therapy with murine-derived proteins.
Reference Range *
<74 ng/mL
Test Limitations
HAMA may be detected in a small percentage of the general population, and usually represent heterophilic antibodies or dietary exposure to murine proteins.
Test Details
Days Set Up
Thursday
Analytic Time
7 - 15 days
Soft Order Code
SLM
Synonyms
- HAMA
Laboratory
Sendout
Reference Laboratory
Quest Valencia 1468
Section
Special Testing
Specimen Requirements
Collection Instructions
Collect specimen in a red top tube. Centrifuge, aliquot serum into a plastic vial and freeze.
Normal Volume
1 mL serum
Minimum Volume
0.5 mL serum
Rejection Criteria
SST is not acceptable
Additional Information
Quest Diagnostics Nichols Institute of Valencia.
Billing
CPT Code
83520
NY State Approved
No