Test Overview
Test Methodology

Plaque Reduction Assay

Test Usage

Measures the extent to which various concentrations of acyclovir inhibit the growth of virus in cell culture. The concentration of drug which results in a 50% reduction in plaque formation induced by viral cytopathic effect (CPE) versus the no-drug control establishes an inhibitory dose (ID-50) drug concentration reportable value.

Test Details
Days Set Up
Tuesday, Wednesday
Analytic Time

17 - 28 days

Soft Order Code
  • Zovirax Resistance
  • HSV Types 1/2 Phenotyping for Acyclovir Drug Resistance
  • Acyclovir Resistance HSV (Phenotype)
  • Herpes Simplex Virus (HSV) Types 1 & 2 Phenotyping for Acyclovir Resistance
Reference Laboratory
Mayo Wild 76 (ZW76) (LabCorp 138370)
Special Testing
Specimen Requirements
Collection Instructions

Acceptable sites for swab collection include: eye, genital,oral, urethral, vesicle or throat. Refrigerate

Normal Volume
1 swab
Minimum Volume
1 swab
Additional Information

Test sent to Mayo Medical Laboratories; performed by LabCorp Burlington.

CPT Code
87252, 87253