Test Overview
Test Methodology

Molecular Assay, Solid Phase Assays

Test Usage

PRA indicates the degree of reactivity of tested serum in terms of percent of positive reactions when tested against a panel of known HLA phenotypes.

Reference Range *

For positive results, the report will define the detected HLA antibody specificities. For negative results, 0% PRA will be reported.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday, 8:00am - 4:30pm
Analytic Time

5 days

Soft Order Code
HLC1L, HLC2L, PRAMO
Synonyms
  • HLA Antibody Screen Mixed
  • HLASM
  • HLA Antibody Screening Class I & II
  • TISSUE TYPING
  • TTYPE
  • HLA REPORT
  • TRANP
  • New Patient for Txf Support
Laboratory
Histocompatibility/Immunogenetics
Section
Histocompatibility
Specimen Requirements
Collection

Collect specimens in sufficient yellow top (ACD) solution A tube AND SST tubes. Send intact specimens at room temperature. Do not refrigerate or freeze.

Normal Volume
20 mL ACD (solution A) whole blood AND 3 mL serum
Minimum Volume
5 mL ACD (solution A) whole blood AND 3 mL serum
Additional Information

The Class I & II screening assay is performed first and detects the presence/absence of HLA antibodies. If the screening assay is positive, a high specificity and sensitivity single HLA Antigen assay will be performed to identify the specificity of the anti-HLA antibody present in the serum sample from the recipient. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated.

Billing
CPT Code
81372, 81375, 86830, 86831
Fee Code
37921,37922,37943
Reflex CPT
86832, 86833
Reflex Fee Code
37962, 37963