Molecular Typing (SSOP)
A severe or even fatal skin reaction has been associated with carbamazepine therapy. Carbamazepine hypersensitivity is significantly more common in patients with HLA-B*1502. This allele is frequent in patients with ancestry from Asia, including South Asian Indians. Patients with ancestry or from these areas should be screened for the HLA-B*1502 allele before treatment with carbamazepine. Treatment with carbamazepine is not recommended for HLA-B*1502 positive patients.
Interpretive report will indicate presence or absence of HLA-B*1502.
- HLA Class I One Locus (High Resolution)
- HLA B*1502
- B1502 Antigen
- Carbamazepine Sensitivity
- HLA REPORT
- TISSUE TYPING
Collect specimen in sufficient yellow top (ACD) solution A or EDTA tubes early in the day. Send intact specimen at room temperature. Do not refrigerate or freeze.