Molecular Typing (SSOP)
Birdshot retinopathy is a rare form of posterior uveitis and accounts for 1-3% of uveitis cases in general. Birdshot retinopathy causes severe, progressive inflammation of both the choroid and the retina. Birdshot retinopathy is the disease with the strongest association to a HLA class I antigen, with more than 95% of patients carrying the HLA-A29 antigen. HLA-A*29:02, which is the most frequent A29 allele in the Caucasian population is also the allele most frequently associated with Birdshot retinopathy in Caucasians. The disease has however been observed in HLA*29:01 Caucasian patients.
Interpretive report will indicate presence or absence of HLA-A29.
The presence of HLA-A29 alone is not sufficient for a diagnosis of Birdshot retinopathy, as there are many cases of patients who do not carry HLA-A29.
- Bird Shot Retinopathy
- Bird Shot Retinopathy - HLA A29
- A29 Antigen
- HLA A-29
- TISSUE TYPING
- HLA REPORT
- HLA Class I One Locus (Low Resolution)
Collect specimen in sufficient yellow top (ACD) solution A or EDTA tubes early in the day. Send intact specimen at room temperature. Do not refrigerate or freeze.