Test Overview
Test Methodology

Molecular Typing (SSOP)

Test Usage

Birdshot retinopathy is a rare form of posterior uveitis and accounts for 1-3% of uveitis cases in general. Birdshot retinopathy causes severe, progressive inflammation of both the choroid and the retina. Birdshot retinopathy is the disease with the strongest association to a HLA class I antigen, with more than 95% of patients carrying the HLA-A29 antigen. HLA-A*29:02, which is the most frequent A29 allele in the Caucasian population is also the allele most frequently associated with Birdshot retinopathy in Caucasians. The disease has however been observed in HLA*29:01 Caucasian patients.

Reference Range *

Interpretive report will indicate presence or absence of HLA-A29.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

The presence of HLA-A29 alone is not sufficient for a diagnosis of Birdshot retinopathy, as there are many cases of patients who do not carry HLA-A29.

Test Details
Days Set Up
Monday - Friday, 8:00am - 4:30pm
Analytic Time

5 days

Soft Order Code
BSHT
MiChart Code
Disease Assoc - BIRD SHOT RETINOPATHY (HLA-A29)
Synonyms
  • BSHT
  • Bird Shot Retinopathy
  • Bird Shot Retinopathy - HLA A29
  • A29 Antigen
  • HLA A-29
  • TTYPE
  • TISSUE TYPING
  • HLA REPORT
  • HLA Class I One Locus (Low Resolution)
Laboratory
Histocompatibility/Immunogenetics
Section
Histocompatibility
Specimen Requirements
Collection

Collect specimen in sufficient yellow top (ACD) solution A or EDTA tubes early in the day. Send intact specimen at room temperature. Do not refrigerate or freeze.

Alternate Specimen
Yellow top ACD Solution B, Green top tube (sodium or lithium heparin) or EDTA
Normal Volume
10 mL ACD (solution A) or EDTA whole blood; additional specimen may be required for patients with extremely low white cell counts.
Minimum Volume
5 mL ACD (solution A) or EDTA whole blood; additional specimen may be required for patients with extremely low white cell counts.
Billing
CPT Code
81373
Fee Code
37924
NY State Approved
No
Resources