Test Overview
Test Methodology

Molecular Typing (SSOP)

Test Usage

Behcet’s disease is a systemic inflammatory vasculitis, characterised by oral ulcers, genital ulcers, skin lesions and ocular lesions. It can affect the blood vessels of almost any system involving the gastrointestinal and neurological systems. The association of HLA-B51 and Behcet's disease has been reported in patients of many ethnic groups. Approximately 20% of healthy individuals of various ethnic origins are HLA-B51 positive, compared to 50 to 80% of patients with Behcet's disease. The principal hypothesis is thus the generating of an immune response by a specific microbial or environmental antigen in a genetically susceptible HLA-B51 individual, causing in the systemic manifestations of Behcet’s disease.

Reference Range *

Interpretive report will indicate presence or absence of HLA-B51.

Test Details
Days Set Up
Monday - Friday, 8:00am - 4:30pm
Analytic Time

5 days

Soft Order Code
BEHC
MiChart Code
Disease Assoc - BEHCETS DISEASE (HLA-B51)
Synonyms
  • Behcet's Disease - HLA B51
  • BEHC
  • Behcets Disease
  • HLA B-51
  • B51 Antigen
  • TTYPE
  • TISSUE TYPING
  • HLA REPORT
  • HLA Class I One Locus (Low Resolution)
  • HLA-B5
Laboratory
Histocompatibility/Immunogenetics
Section
Histocompatibility
Specimen Requirements
Collection

Collect specimen in sufficient yellow top (ACD) solution A tubes early in the day. Send intact specimen at room temperature. Do not refrigerate or freeze.

Alternate Specimen
Yellow top ACD Solution B, Green top tube (sodium or lithium heparin).
Normal Volume
10 mL ACD (solution A) whole blood; additional specimen may be required for patients with extremely low white cell counts.
Minimum Volume
5 mL ACD (solution A) whole blood; additional specimen may be required for patients with extremely low white cell counts.
Billing
CPT Code
81373
Fee Code
37924
NY State Approved
No