Test Overview
Test Methodology

Solid Phase Assays

Test Usage

In addition to HLA typing, patients are screened for HLA antibodies. Panel reactivity antibody (PRA) indicates the degree of reactivity of tested serum in terms of percent of positive reactions when tested against a panel of known HLA phenotypes.

Reference Range *

For positive results, the report will define the detected HLA antibody specificities. For negative results, 0% PRA will be reported.

*Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday, 8:00am - 4:30pm
Analytic Time

5 days

Soft Order Code
HLPRA
MiChart Code
LAB7618 HLA Antibody Screen
Laboratory
Histocompatibility/Immunogenetics
Section
Histocompatibility
Specimen Requirements
Collection Instructions

Collect specimen in a red top (preferred) or SST tube. Send intact specimen at room temperature. Do not refrigerate or freeze.

Normal Volume
5mL serum
Minimum Volume
3 mL serum
Additional Information

The Class I & II screening assay is performed first and detects the presence/absence of HLA antibodies. If the screening assay is positive, a high specificity and sensitivity single HLA Antigen assay will be performed to identify the specificity of the anti-HLA antibody present in the serum sample from the recipient. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated.

Billing
CPT Code
86830, 86831
Fee Code
37940, 37941
Reflex CPT
86832, 86833
Reflex Fee Code
37962, 37963
NY State Approved
No