Test Overview
Immunoassay
Documentation of immediate hypersensitivity reactions or diagnosis of patients with systemic mastocytosis. Elevated values are seen in patients with anaphylaxis, with urticaria, or following provocative skin tests.
0.006 - 0.131 mg/24 hour
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
False negatives may occur if collection of the specimen is not performed near the time of allergic reactions.
Test Details
6 - 13 days
Specimen Requirements
Collect 24 hour urine specimen. Add 10 mL of 6 N HCl to container prior to start of collection. Specimens with no preservative are also acceptable: add HCl to container following collection, mix well and send 4 mL aliquot (preferred); alternatively a non-acidified aliquot will be accepted. Patient should avoid antihistamines, oral corticosteroids, and substances that block H2 receptors for at least 24 hours prior to specimen collection.
Patient Preparation: Avoid direct sunlight. Patient should refrain from taking allergy causing drugs, antihistamines, oral corticosteroids, and substances which block H2 receptors for at least 24 hours prior to specimen collection. Collect urine for 24 hours in a container with 10 mL HCl. Send to Specimen Processing refrigerated
Patient should avoid antihistamines, oral corticosteroids, and substances that block H2 receptors for at least 24 hours prior to specimen collection. And remain out of direct sunlight
Additional Information
Test sent to Mayo Medical Laboratories; performed by Quest Nichols Institute.