Test Overview
Test Methodology

Isotachophoresis with Laser-Induced Fluorescence

Test Usage

This test includes a GALAD (gender, age, alpha-fetoprotein [AFP]-L3, AFP, des-gamma-carboxy prothrombin [DCP]) model score calculation to calculate the probability of hepatocellular carcinoma (HCC). The GALAD model has been demonstrated to have higher diagnostic accuracy for the detection of HCC when compared to the use AFP, AFP-L3, and DCP markers alone or in combination. The performance of the GALAD score has also been reported to be superior to ultrasound for HCC detection.

Reference Range *

TOTAL ALPHA-FETOPROTEIN (AFP):<4.7 ng/mL
AFP L3-PERCENT:<10%
DES-GAMMA-CARBOXY PROTHROMBIN:<7.5 ng/mL
GAL1:Not applicable
GAL2:Not applicable

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday, Wednesday, Friday
Analytic Time

2 - 5 days

Soft Order Code
MHCCG
Synonyms
    Laboratory
    Sendout
    Reference Laboratory
    Mayo HCCGS
    Section
    Special Testing
    Specimen Requirements
    Collection

    Gender and age are required

    Collection Instructions

    Collect specimen in an SST or red top tube. Spin and aliquot into a screw capped plastic tube. Send to Specimen Processing frozen

    Contraindications
    GALAD score testing (this test) should not be performed for pregnant patients as alpha-fetoprotein results are elevated during pregnancy.
    Normal Volume
    0.5 mL serum
    Minimum Volume
    0.25 mL sserum
    Storage Temperature
    Frozen preferred, refrigerated acceptable
    Rejection Criteria
    Gross hemolysis
    Additional Information

    Test performed by Mayo Clinic Laboratories

    Billing
    CPT Code
    82107, 83951
    Fee Code
    AB082, AB083
    NY State Approved
    No