Test Overview
Test Methodology

Isotachophoresis with Laser-Induced Fluorescence

Test Usage

This test includes a GALAD (gender, age, alpha-fetoprotein [AFP]-L3, AFP, des-gamma-carboxy prothrombin [DCP]) model score calculation to calculate the probability of hepatocellular carcinoma (HCC). The GALAD model has been demonstrated to have higher diagnostic accuracy for the detection of HCC when compared to the use AFP, AFP-L3, and DCP markers alone or in combination. The performance of the GALAD score has also been reported to be superior to ultrasound for HCC detection.

Reference Range *

TOTAL ALPHA-FETOPROTEIN (AFP):<4.7 ng/mL
AFP L3-PERCENT:<10%
DES-GAMMA-CARBOXY PROTHROMBIN:<7.5 ng/mL
GAL1:Not applicable
GAL2:Not applicable

Test Details
Days Set Up
Monday, Wednesday, Friday
Analytic Time

2 - 5 days

Soft Order Code
HCCGS
Laboratory
Sendout
Reference Laboratory
Mayo HCCGS
Section
Special Testing
Specimen Requirements
Collection

Gender and age are required

Collection Instructions

Collect specimen in a red top or SST tube. Spin and aliquot into a screw capped plastic tube. Send to Specimen Processing frozen

Contraindications
GALAD score testing (this test) should not be performed for pregnant patients as alpha-fetoprotein results are elevated during pregnancy.
Normal Volume
0.5 mL serum
Minimum Volume
0.25 mL sserum
Storage Temperature
Frozen preferred, refrigerated acceptable
Rejection Criteria
Gross hemolysis
Additional Information

Test performed by Mayo Clinic Laboratories

Billing
CPT Code
82107, 83951
NY State Approved
No