Diagnosis of acute or recent (<6 months) hepatitis E infection.
Negative. Borderline results may be seen in: 1) acute hepatitis E infection with rising level of anti-hepatitis E virus (HEV) IgM; 2) recent hepatitis E infection with declining level of anti-HEV IgM; or 3) cross-reactivity with nonspecific antibodies (ie, false-positive results).
A negative test result does not exclude the presence of recent hepatitis E infection, especially in immunocompromised patients. Repeat testing of serum for anti-HEV IgM in 2 to 4 weeks may be necessary for diagnosis of acute in such patients.
5 - 9 days
- Hepatitis E, IgM
Collect specimen in an SST tube. Centrifuge, aliquot serum into a plastic vial and freeze.
Test sent to Mayo Medical Laboratories. If hepatitis E virus (HEV) IgM antibody screen is reactive or borderline, HEV IgM antibody confirmation (HEVML) will be performed at an additional charge. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated.