By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Hematopoietic cell transplants (HCT) is a potentially curative therapy for cancers of the blood and bone marrow, including leukemias, lymphomas, and multiple myeloma. Use of HCT has increased as new techniques have allowed for transplantation in patients who previously would not have been considered HCT candidates. Among the most important factors that affect the outcome of the HCT is the degree of human leukocyte antigen (HLA) matching between the recipient and the related or unrelated donor, or cord blood unit. HLA matching plays an important role in engraftment, occurrence and severity of graft-versus-host disease (GVHD) and overall survival.