Test Overview
Test Methodology

Inductively Coupled Plasma/Mass Spectrometry

Test Usage

Detecting arsenic, cadmium, mercury, and lead exposure and toxicity in 24-hour urine specimen.

Reference Range *

ARSENIC: 0-17 years: not established, > or =18 years: <18 mcg/24 hour;
CADMIUM: 0-17 years: not established, > or =18 years: <0.6 mcg/24 hour;
MERCURY: 0-17 years: not established, > or =18 years: <2 mcg/24 hour, Toxic concentration: >50 mcg/24 hour; The concentration at which toxicity is expressed is widely variable between patients. 50 mcg/24 hour is the lowest concentration at which toxicity is usually apparent.
LEAD: 0-17 years: not established, > or =18 years: <1 mcg/24 hour.

Test Details
Days Set Up
Monday - Saturday
Analytic Time

1 - 5 days

Soft Order Code
HMU24
MiChart Code
Heavy Metals Screen, Urine
Synonyms
  • Arsenic (As), Urine
  • Cadmium (Cd), Urine
  • Lead (Pb), Urine
  • Mercury (Hg), Urine
  • Metals, Urine
  • HEAVY METAL SCREEN, URINE 24H
  • AS-U
  • CD-U
  • PB-U
  • HG-U
  • HMSU
Laboratory
Sendout
Reference Laboratory
Mayo HMU24
Section
Special Testing
Specimen Requirements
Collection Instructions

Collect 24 hour urine in a clean, plastic container with no metal cap or glued insert and no preservative. Aliquot urine into a clean, plastic container with no metal cap or glued insert and refrigerate within 4 hours of completion of collection. Record 24 hour urine volume and collection dates/times on the request form. Patient should not eat seafood for a 48 hour period prior to start of collection. Collection must take place prior to or 48 hours after administering gadolinium-containing contrast media. If the patient is an Ohio resident, complete the appropriate sections of the Ohio Lead Reporting Form and submit with the specimen.

Contraindications
Do not collect specimens from patients who have received gadolinium within the past 48 hours. Gadolinium, a material contained in some contrast media, is known to interfere with most metals tests.
Normal Volume
10 mL aliquot of 24 hour urine collection
Minimum Volume
3 mL aliquot of 24 hour urine collection
Additional Information

Includes: Cadmium (Cd), Arsenic (As), Lead (Pb), Mercury (Hg). If arsenic concentration is 35 mcg/L or greater, then fractionation (MASFR) will be performed at an additional charge. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Test sent to Mayo Medical Laboratories.

Billing
CPT Code
82175 Arsenic, 82300 Cadmium, 83655 Lead, 83825 Mercury
Fee Code
AA282, AA283, AA284, AA281
Reflex CPT
82175
Reflex Fee Code
32111
LOINC
Z180-0
NY State Approved
No