Two major groups of hantaviruses are recognized based on clinical presentation. The first group includes Sin Nombre Virus (SNV), which causes hantavirus pulmonary syndrome, a severe and possibly fatal form of acute respiratory distress. A second group of hantaviruses (including Seoul, Hantaan, Dobrava, and Puumala viruses) causes hemorrhagic fever with renal syndrome, a condition not typically seen in the United States.
2 - 8 days
- Sin Nombre Virus Antibodies
Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.
Sera are initially screened for IgG and IgM antibodies recognizing the nucleocapsid protein common to all hantaviruses. All screen IgM positive samples are then tested for SNV-specific IgM at an additional charge; further, any screen IgM positive samples that are also screen IgG positive are tested for SNV-specific IgG at an additional charge. A positive result in the screening ELISA but a negative result in confirmatory assays may indicate reactivity to a hantavirus causing hemorrhagic fever with renal syndrome. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Test sent to Mayo Medical Laboratories; performed by Focus Diagnostics.