Direct Enzyme Immunoassay (EIA)
Growth Hormone Releasing Hormone is a 44 amino acid peptide produced primarily by the hypothalamus. It is a neurohumoral control for adenohypophyseal secretion of Growth Hormone. Other hypothalamic hormones have a stimulatory effect on pituitary hormones, but Growth Hormone Releasing Hormone has no known effect on other pituitary hormones. Somatostatin is the inhibitory counterpart of Growth Hormone Releasing Hormone. Growth Hormone Releasing Hormone has structural similarities with the Secretin-Glucagon family of gastrointestinal hormones. Growth Hormone Releasing Hormone has been isolated from pancreatic Islet Cells and various cancer tumor cells.
Levels of IR-GH-RH
Baseline range: 5-18 pg/mL
Levels in GH-RH Dysfunction:
Patients with acromegaly: up to 200 pg/mL
Patients with small cell lung carcinoma: up to 50 pg/mL
GH-RH secreting tumors: 200-10,000 pg/mL
5 - 9 days
Test sent to Mayo Medical Laboratories; performed by Interscience Institute.