Test Overview
Test Methodology

Direct Enzyme Immunoassay (EIA)

Test Usage

Growth Hormone Releasing Hormone is a 44 amino acid peptide produced primarily by the hypothalamus. It is a neurohumoral control for adenohypophyseal secretion of Growth Hormone. Other hypothalamic hormones have a stimulatory effect on pituitary hormones, but Growth Hormone Releasing Hormone has no known effect on other pituitary hormones. Somatostatin is the inhibitory counterpart of Growth Hormone Releasing Hormone. Growth Hormone Releasing Hormone has structural similarities with the Secretin-Glucagon family of gastrointestinal hormones. Growth Hormone Releasing Hormone has been isolated from pancreatic Islet Cells and various cancer tumor cells.

Reference Range *

Levels of IR-GH-RH
Baseline range: 5-18 pg/mL
Levels in GH-RH Dysfunction:
Patients with acromegaly: up to 200 pg/mL
Patients with small cell lung carcinoma: up to 50 pg/mL
GH-RH secreting tumors: 200-10,000 pg/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday
Analytic Time

11 - 15 days

Soft Order Code
  • GH-RH
Reference Laboratory
Mayo FIRGH (90161) (Interscience)
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and freeze.

Normal Volume
3 mL serum
Minimum Volume
1 mL serum
Additional Information

Test sent to Mayo Medical Laboratories; performed by Interscience Institute.

CPT Code