If the screen is positive, a titer will be performed at an additional charge. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Test includes pathologist interpretation of results billed as a separate additional charge. This test is not available without interpretation. The two principal mechanisms of autoimmune renal disease are those of immune complex deposition with complement activation and those due to antibodies to the renal glomerular basement membrane.