Test Overview
Test Methodology

Custom targeted genomic enrichment and massively parallel sequencing panel as well as multiplex ligation-dependent probe amplification (MLPA)

Test Usage

DNA test for TTP, aHUS, HUS, DDD, C3G. Test is a panel of: CFH, CFI, MCP, CFB, CFHR5, C3, THBD, ADAMTS13, PLG, DGKE, G6PD, MMACHC, MPLA

Reference Range *

Interpretive report provided

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday
Analytic Time

3-4 weeks

Soft Order Code
Reference Laboratory
University of Iowa, Molecular Otolaryngology & Renal Research Laboratories
Special Testing
Specimen Requirements

Collect EDTA tube. Send to specimen Processing as whole blood- do not spin, room temperature. If collected on a Friday, specimen may be refrigerated over the weekend for Monday shipment

Alternate Specimen
DNA: 10 μg DNA; minimum concentration: 50 ng/μl (A260/A280 1.8-2) resuspended in 0.1mM EDTA (10mM Tris HC1, 0.1mM EDTA, pH 8, Teknova Cat#T0220)
Normal Volume
8 -10 mL EDTA whole blood
Minimum Volume
4 mL EDTA whole blood
Storage Temperature
Ambient; Refrigerated if storing over a weekend
Additional Information

Test performed by University of Iowa, Molecular Otolaryngology & Renal Research Laboratories

CPT Code
81405, 81479