Label a CytoLyt container with the patient's last name, first name and registration number (or other second unique patient identifier). Brush lesion area. Place brush directly into CytoLyt, swirl the brush vigorously in the solution, then snip into the container. Submit with an appropriately completed requisition, including pertinent patient history. Refrigerate specimens that cannot be delivered immediately and deliver as soon as possible. Do not allow specimen to freeze. If CytoLyt is not available, label a slide with patient's last name, first name and registration number (or other second unique patient identifier) using a graphite pencil (do not use ink, wax or crayon). Gently roll brush on glass slide to cover the area of a dime and fix each smear immediately with spray fixative. Allow spray-fixed slides to dry completely and place into a slide holder. Submit with an appropriately completed requisition, including pertinent patient history.